Lintasan nonmevalonat

Lintasan nonmevalonat, yang juga disebut sebagai jalur independen mevalonat atau jalur MEP/DOXP, adalah suatu lintasan metabolisme alternatif untuk pembentukan prekursor isoprenoid, yaitu isopentenil pirofosfat (IPP) dan dimetilalil pirofosfat (DMAPP).[1]Pada sel tumbuhan, pembentukan IPP/DMAPP melalui lintasan berlangsung di dalam organel plastid, sementara pembentukan melalui lintasan MVA terjadi di sitoplasma.[2]Sebagian besar bakteri gram-negatif, bakteri fotosintetik sianobakteri dan alga hijau hanya menggunakan jalur MEP.[3]

Referensi

  1. ^ Rohdich, Felix; Kis, Klaus; Bacher, Adelbert; Eisenreich, Wolfgang (2001-10-01). "The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates". Current Opinion in Chemical Biology. 5 (5): 535–540. doi:10.1016/S1367-5931(00)00240-4. ISSN 1367-5931. 
  2. ^ Lichtenthaler, Hartmut K. (1999-06). "THE 1-DEOXY-D-XYLULOSE-5-PHOSPHATE PATHWAY OF ISOPRENOID BIOSYNTHESIS IN PLANTS". Annual Review of Plant Physiology and Plant Molecular Biology (dalam bahasa Inggris). 50 (1): 47–65. doi:10.1146/annurev.arplant.50.1.47. ISSN 1040-2519. 
  3. ^ Vranová, Eva; Coman, Diana; Gruissem, Wilhelm (2013-04-29). "Network Analysis of the MVA and MEP Pathways for Isoprenoid Synthesis". Annual Review of Plant Biology (dalam bahasa Inggris). 64 (1): 665–700. doi:10.1146/annurev-arplant-050312-120116. ISSN 1543-5008. 

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