Interféron alfa

Interféron alfa
Image illustrative de l’article Interféron alfa
Identification
Code ATC L03AB01
modifier 

L'interféron alfa est un groupe de médicaments utilisés pour traiter un certain nombre de cancers et d'infections virales [1].

Usage médical

Les cancers pour lesquels il est utilisé comprennent le rein, le mélanome, le myélome multiple, la leucémie, le sarcome de Kaposi et le lymphome non hodgkinien [2]. Les types d'infections pour lesquelles il est utilisé comprennent l'hépatite B et l'hépatite C. [1] Il est généralement administré par injection sous la peau[2].

Effets secondaires

Les effets secondaires courants comprennent la fièvre, les maux de tête, les douleurs articulaires, la fatigue, la perte de cheveux, la dépression, l'essoufflement et le faible nombre de globules blancs [3], plus loin effets secondaires peuvent inclure des problèmes de foie et une pancréatite [1],[3] Il s'agit d'une cytokine normalement produite par le système immunitaire [1],il existe un certain nombre de types, notamment l'interféron alfa-2a, l'interféron alfa-2b et l'interféron alfa-n3 [1],[3] Ceux-ci peuvent être pégylés ( peginterféron alfa-2a et alfa-2b ) pour prolonger leur durée d'effet[1].

Histoire

L'interféron alfa a été approuvé pour un usage médical aux États-Unis dans les années 1980 pour le cancer et dans les années 1990 pour l'hépatite B et C. La version pégylée est devenue disponible en 2000. L'interféron alfa-2a n'est plus fabriqué. Au Royaume-Uni, le peginterféron alfa-2a est disponible dans le commerce[1],[4],[5]

Références

  1. ↑ a b c d e f et g « Alpha Interferon » [archive du ], LiverTox: Clinical and Research Information on Drug-Induced Liver Injury, National Institute of Diabetes and Digestive and Kidney Diseases, (consulté le )
  2. ↑ a et b « Interferon alfa | Cancer information | Cancer Research UK » [archive du ], www.cancerresearchuk.org (consulté le )
  3. ↑ a b et c (en) « Interferon Alfa Monograph for Professionals » [archive du ], Drugs.com (consulté le )
  4. ↑ BNF 81 : March - September 2021, London, BMJ Group and the Pharmaceutical Press, (ISBN 978-0857114105), p. 664
  5. ↑ (en) « Roferon-A, Interferon alfa-2a recombinant, injectable solution, 1mL », sur National Museum of American History (consulté le )

Read other articles:

Terong, Dlingo, Bantul

TerongKalurahanNegara IndonesiaProvinsiDaerah Istimewa YogyakartaKabupatenBantulKecamatanDlingoKode Kemendagri34.02.11.2005 Luas788.671,5 Ha[1]Jumlah penduduk-Kepadatan- Terong (Jawa: Térong) adalah desa di Kecamatan Dlingo, Bantul, Daerah Istimewa Yogyakarta, Indonesia yang terletak paling Utara dari Kecamatan Dlingo. Desa ini merupakan desa yang secara politik paling dinamis dibanding desa-desa lainnya di Kecamatan Dlingo, hal ini bisa ditunjukkan dengan partisipasi politi...

 

Footballers' Wives: Extra Time

Television series This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Footballers' Wives: Extra Time – news · newspapers · books · scholar · JSTOR (February 2019) (Learn how and when to remove this template message) Footballers' Wives: Extra TimeOpening credits titleAlso known asFootballers' Wives: OvertimeCreat...

 

Daftar kabupaten dan kota di Banten

Lambang Banten Peta lokasi Banten di Indonesia Peta kabupaten di Banten Provinsi Banten terdiri atas 4 kabupaten dan 4 kota. Ibu kotanya adalah Kabupaten Serang. Banten sebelumnya merupakan bagian dari Provinsi Jawa Barat, yang kemudian dimekarkan sebagai provinsi pada tanggal 17 Oktober 2000. Berikut adalah daftar kabupaten dan kota di Banten, beserta pusat pemerintahan kabupaten. Berikut daftar kabupaten dan/atau kota di Banten No. Kabupaten/kota Ibu kota Bupati/wali kota Luas wilayah (km�...

Lucio Blanco

Lucio BlancoLucio Blanco in 1914Born(1879-07-21)July 21, 1879DiedJune 1922NationalityMexicanOccupationMilitary OfficerKnown forParticipation in the Mexican Revolution of 1910 to 1920 Blanco and staff circa 1913 Lucio Blanco (July 21, 1879 – June 1922) was a Mexican military officer and revolutionary, noteworthy for his participation in the Mexican Revolution of 1910 to 1920. Biography Lucio Blanco was born on July 21, 1879, in Nadadores, Coahuila.[1] He is noted for three major...

 

Hans Kuhn (philologist)

German philologist (1899–1988) Hans KuhnBorn(1899-07-13)13 July 1899Minden, GermanyDied8 October 1988(1988-10-08) (aged 89)Kiel, GermanyNationalityGermanAcademic backgroundAlma mater University of Münster Academic advisorsKarl HelmInfluencesJan de VriesAcademic workDiscipline Germanic philology Sub-discipline Nordic philology Institutions University of Münster University of Leipzig University of Berlin University of Kiel Notable students Klaus von See Dietrich Hofmann Main interests ...

 

List of deputy prime ministers of Suriname

Deputy Prime Minister of SurinameVice-minister-president van SurinameLongest serving officeholderOlton van Genderen24 December 1973 – 25 February 1980StatusDeputy prime ministerMember ofCabinet of SurinameReports toPrime Minister of SurinameSeatParamariboNominatorPrime Minister of SurinameFormation25 June 1958First holderAlfred Morpurgo [nl]Final holderHarry KensmilAbolished25 January 1988SuccessionDeputy Vice President of Suriname The Deputy Prime Minister of Suriname (Dutch:...

Acting President of the Quorum of the Twelve Apostles

Leadership position in the Church of Jesus Christ of Latter-day Saints This article relies largely or entirely on a single source. Relevant discussion may be found on the talk page. Please help improve this article by introducing citations to additional sources.Find sources: Acting President of the Quorum of the Twelve Apostles – news · newspapers · books · scholar · JSTOR (February 2019) Acting President of the Quorum of the Twelve Apostles is a pries...

 

Castello di Ancy-le-Franc

Castello di Ancy-le-FrancVeduta del castelloLocalizzazioneStato Francia RegioneBorgogna LocalitàAncy-le-Franc Coordinate47°46′26″N 4°09′42″E / 47.773889°N 4.161667°E47.773889; 4.161667Coordinate: 47°46′26″N 4°09′42″E / 47.773889°N 4.161667°E47.773889; 4.161667 Informazioni generaliCondizioniIn uso Costruzione1544 - 1550 Stilerinascimentale e Rinascimento francese UsoProprietà privata; aperto ai visitatori RealizzazioneArchitettoSe...

 

Krung Thai Bank

Krung Thai Bank PLCJenisPublikKode emitenSET: KTBIndustriPerbankanDidirikan14 Maret 1966 (1966-03-14) [1]Kantorpusat35 Sukhumvit Road, Khlong Toei Nuea, Wattana, Bangkok, Thailand [2]Wilayah operasi ThailandPendapatan BT฿ 132,53 miliar (2013)[3]Laba bersih BT฿ 33,93 miliar (2013)[3]Total aset BT฿ 2.514,77 miliar (2013)[3]Total ekuitas BT฿ 206,09 miliar (2013)[3]PemilikBank of ThailandKaryawan18.032 (2010)[3]Situs webwww...

Військово-музичне управління Збройних сил України

Військово-музичне управління Збройних сил України Тип військове формуванняЗасновано 1992Країна  Україна Емблема управління Військово-музичне управління Збройних сил України — структурний підрозділ Генерального штабу Збройних сил України призначений для планува...

 

Pemilihan Gubernur Jawa Barat 2003

Pemilihan Gubernur Jawa Barat 20031998200822 Mei 2003100 suara anggota Dewan Perwakilan Rakyat Daerah Jawa BaratDitetapkan berdasarkan perolehan suara terbanyak untuk menangKandidat   Calon Danny Setiawan Tayo Tarmadi Partai Partai Golongan Karya PDI-P Pendamping Nu'man Abdul Hakim Rudi Harsya Tanaya Suara elektoral 49 39 Gubernur petahanaRaden Nana Nuriana Golongan Karya Gubernur terpilih Danny Setiawan Partai Golongan Karya Pemilihan Gubernur Jawa Barat 2003 adalah pemilihan yang...

 

Incarnation

Deity or divine being in human/animal form on Earth Incarnations redirects here. For other uses, see Incarnations (disambiguation). Further information: Epic cycles of incarnations Incarnation literally means embodied in flesh or taking on flesh. It is the conception and the embodiment of a deity or spirit in some earthly form[1] or an anthropomorphic form of a god.[2] It is used to mean a god, deity, or Divine Being in human or animal form on Earth. The proper noun, Incarnati...

Leonora LaPeter Anton

American journalist Leonora LaPeter AntonOccupationJournalistNationalityAmericanAlma materUniversity of Illinois at Urbana–ChampaignNotable awardsPulitzer Prize for Investigative Reporting 2016 Insane. Invisible. In Danger – co-author Children1 Leonora LaPeter Anton is an American journalist with the Tampa Bay Times. Anton was a co-recipient of the 2016 Pulitzer Prize for Investigative Reporting.[1] Biography Anton grew up in Connecticut, but spent a lot of her childhood livi...

 

Rigel

Untuk kegunaan lain, lihat Rigel (disambiguasi). Rigel Rigel di rasi bintang Orion (dilingkari) Data pengamatan Epos J2000.0      Ekuinoks J2000.0 Rasi bintang Orion Pengucapan /ˈraɪdʒəl/[1] or /-ɡəl/[2] A Asensio rekta  05j 14m 32.27210d[3] Deklinasi  −08° 12′ 05.8981″[3] Magnitudo semu (V) 0.13[4] (0.05–0.18[5]) BC Asensio rekta  05j 14m 32.049d[6]...

 

سقاية حسين باشا

هذه المقالة بحاجة لصندوق معلومات. فضلًا ساعد في تحسين هذه المقالة بإضافة صندوق معلومات مخصص إليها. سقاية حسين باشا هذه السقاية ربما سميت بسقاية حسين باشا نسبة إلى حسين باشا والي بغداد سنة 1650م، خلال حكم الدولة العثمانية والتي كانت مخصصة للنفع العام في بغداد، وقد اشار اليها �...

User talk:Andrew Davidson

This is Andrew Davidson's personal talk page.Please edit this page to leave me a message but note that the Visual Editor does not work on such talk pages and so you will have to use the original Wikitext editor. The simplest way of doing this is to start a new section by using the standard link above or by clicking here. Old discussions and messages are subject to regular housekeeping. Archives are organised mainly by topic (see right). Archives 2011–20142015–20182019–2022AccoladesAnim...

 

Accuracy and precision

Characterization of measurement error Accuracy is the proximity of measurement results to the accepted value; precision is the degree to which repeated (or reproducible) measurements under unchanged conditions show the same results. Accuracy and precision are two measures of observational error. Accuracy is how close a given set of measurements (observations or readings) are to their true value. Precision is how close the measurements are to each other. The International Organization for Stan...

 

أساطير فارسية

تحتاج النصوص المترجمة في هذه المقالة إلى مراجعة لضمان معلوماتها وإسنادها وأسلوبها ومصطلحاتها ووضوحها للقارئ، لأنها تشمل ترجمة اقتراضية أو غير سليمة. فضلاً ساهم في تطوير هذه المقالة بمراجعة النصوص وإعادة صياغتها بما يتناسب مع دليل الأسلوب في ويكيبيديا. هذه واحدة من سلسلة ...

Gross pathology

Macroscopic (visible) signs of disease on organs and other body parts Gross pathology of miliary tuberculosis. Gross pathology refers to macroscopic manifestations of disease in organs, tissues, and body cavities. The term is commonly used by anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy. In the intricate process of anatomical pathology, the grossing stage plays a pivotal role. It is v...

 

2016–17 Ekstraklasa

81st season of top-tier football league in Poland Football league seasonEkstraklasaSeason2016–17Dates15 July 2016 – 4 June 2017ChampionsLegia Warsaw(12th title)RelegatedGórnik ŁęcznaRuch ChorzówChampions LeagueLegia WarsawEuropa LeagueArka GdyniaJagiellonia BiałystokLech PoznańMatches played296Goals scored812 (2.74 per match)Top goalscorerMarco PaixãoMarcin Robak(18 goals)Biggest home winCracovia 6–0 Korona(2 October 2016)Śląsk 6–0 Ruch(13 May 2017)Legia 6–0 Termalica(...