Sekobarbitaali

Sekobarbitaali
Sekobarbitaali
Systemaattinen (IUPAC) nimi
5-[(2R)-pentan-2-yyli]-5-prop-2-enyyli-1,3-diatsinaani-2,4,6-trioni
Tunnisteet
CAS-numero 76-73-3
ATC-koodi N05CA06
PubChem CID 5193
DrugBank DB00418
Kemialliset tiedot
Kaava C12H18N2O3 
Moolimassa 238.283 g/mol
SMILES Etsi tietokannasta: eMolecules, PubChem
Farmakokineettiset tiedot
Hyötyosuus ?
Proteiinisitoutuminen 45–60 %
Metabolia hepaattinen
Puoliintumisaika 15–40 tuntia
Ekskreetio Renaalinen
Terapeuttiset näkökohdat
Raskauskategoria

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Reseptiluokitus


Antotapa Oraalinen

Sekobarbitaali (5-allyyli-5-(1-metyylibutyyli)-barbituurihappo) on barbituraatteihin kuuluva lääkeaine, jota käytetään muun muassa anestesia-, epilepsia-, uni- ja rauhoittavana lääkkeenä. Lääkettä myydään Eli Lilly and Company -yhtiön valmistamana nimillä Seconal ja Tuinal. Tuinal sisältää myös amobarbitaalia. Käytöstä poistuneessa Vesparax-nimisessä yhdistelmälääkkeessä oli 150 mg sekobarbitaalia, 50 mg brallobarbitaalia ja 50 mg hydroksitsiinia.[1] Sekobarbitaali on määritelty huumausaineeksi Euroopan talousalueella.[2]

Sekobarbitaalia käytetään myös eläinlääketieteessä eutanasiassa.lähde?

Käyttöön liittyviä kuuluisia kuolemia

Lähteet

  1. ↑ Lhermann J.: Clinical application of a new very active hypnotic associating sodium secobarbital, calcium brallobarbital and hydroxyzine (UC-8130). Gazette Medicale de France. 1964 Mar 10;71:961-2. (englanniksi)
  2. ↑ Valtioneuvoston asetus huumausaineina… 1128/2015 Finlex Säädökset alkuperäisinä: finlex.fi. Viitattu 13.9.2020.
  3. ↑ Thomson, David,Film Studies: She couldn't act for toffee - until she burst into song (Arkistoitu – Internet Archive); The Independent 27.6.2004. (englanniksi)
  4. ↑ Tennessee Williams' death myth (Arkistoitu – Internet Archive) New York Post 15.2.2010 (englanniksi)
  5. ↑ Tweedie,Neil: Shah's daughter stole to fuel her drug habit 26.7.2001. Telegraph.co.uk. Viitattu 23.7.2012. (englanniksi)
  6. ↑ Celebrity Sightings - B Bankruptcy & Debt Information from Doney & Associates. Viitattu 23.7.2012. (englanniksi)
  7. ↑ The truth about the night Hendrix died of an overdose (Arkistoitu – Internet Archive) The Sunday Times (englanniksi)
  8. ↑ Mar Centenera: Medio siglo sin Pizarnik, la poeta que escribía contra el miedo El País Argentina. 25.9.2022. Viitattu 23.3.2024. es-ar

Aiheesta muualla

Barbituraatit
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