S1PR3
گیرندهٔ شمارهٔ ۳ اسفنگوزین-۱-فسفات (انگلیسی: Sphingosine-1-phosphate receptor 3) یا به اختصار S1PR3، یک پروتئین است که در انسان توسط ژن «S1PR3» کُدگذاری میشود.
این پروتئین نوعی گیرنده جفتشونده با پروتئین جی است که به مولکول لیپیدی پیامرسان اسفنگوزین-۱-فسفات متصل میشود و از این جهت گاهی نیز، S1P3 نامیده میشود.[۴] محصول نهایی در تنظیم رگزایی و عملکرد لایهٔ درونرگی نقش دارد.[۴]
منابع
- ↑ ۱٫۰ ۱٫۱ ۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000067586 - Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ ۴٫۰ ۴٫۱ "Entrez Gene: S1PR3 sphingosine-1-phosphate receptor 3".
- مشارکتکنندگان ویکیپدیا. «S1PR3». در دانشنامهٔ ویکیپدیای انگلیسی، بازبینیشده در ۲۰ اوت ۲۰۱۹.
برای مطالعهٔ بیشتر
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- Takuwa Y (2002). "[Regulation of Rho family G proteins and cell motility by the Edg family of sphingosin 1-phosphate receptors]". Tanpakushitsu Kakusan Koso. 47 (4 Suppl): 496–502. PMID 11915348.
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- An S, Bleu T, Huang W, et al. (1998). "Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids". FEBS Lett. 417 (3): 279–82. doi:10.1016/S0014-5793(97)01301-X. PMID 9409733.
- Van Brocklyn JR, Tu Z, Edsall LC, et al. (1999). "Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218". J. Biol. Chem. 274 (8): 4626–32. doi:10.1074/jbc.274.8.4626. PMID 9988698.
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- Windh RT, Lee MJ, Hla T, et al. (1999). "Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins". J. Biol. Chem. 274 (39): 27351–8. doi:10.1074/jbc.274.39.27351. PMID 10488065.
- Goetzl EJ, Dolezalova H, Kong Y, et al. (1999). "Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer". Cancer Res. 59 (20): 5370–5. PMID 10537322.
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پیوند به بیرون
- Lysophospholipid receptors در سرعنوانهای موضوعی پزشکی (MeSH) در کتابخانهٔ ملی پزشکی ایالات متحدهٔ آمریکا
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