MAP cinasa cinasa

MAP cinasa cinasa
Estructuras disponibles
PDB
 Estructuras enzimáticas
Identificadores
Identificadores
externos
Número EC 2.7.12
Estructura/Función proteica
Tipo de proteína Cinasa
Funciones Enzima
Ortólogos
Especies
Humano Ratón
Ubicación (UCSC)
n/a n/a
PubMed (Búsqueda)
[1]


PMC (Búsqueda)
[2]

Las MAP cinasa cinasas, también conocidas como MAP2K, son enzimas con actividad proteína cinasa que fosforilan a las MAP cinasas. Se clasifican con el número EC 2.7.12.2. Se han descrito hasta ahora siete genes que codifican proteínas pertenecientes a este tipo de cinasas:

Los activadores de la MAP cinasa p38 (MKK3 y MKK4), de JNK (MKK4) y de ERK (MEK1 y MEK2) definen una ruta de transducción de señales independiente de las MAPK.[1]

Referencias

Enlaces externos

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