Ntuli was a leader of the South Durban region of the African National Congress. He played a crucial role in ensuring the presence of the ANC in rural communities in KwaZulu-Natal and building relations with traditional leaders.[2]
Ntuli stood for election to the South African National Assembly in the 2009 general elections as a candidate on the ANC's list of parliamentary candidates from KwaZulu-Natal and was elected and sworn in on 6 May 2009.[3][4] He was a member of the Portfolio Committee on Economic Development during his tenure in parliament.[5]