Zelikovitch (Hebrew: זליקוביץ׳, Yiddish: זעליקאָוויטש, Polish: Zelikowicz), also spelled Zelikovich or Zelikowitz, is an Ashkenazi Jewish surname. It is derived from the Yiddish-language personal name Zelig. The Slavic suffix "-ovich" means "son of".

The surname may refer to:

• Getzel Zelikovitch [he], Egyptologist, writer, journalist and translator
• Elimelekh Zelikovich [he], commander of the first instructors' course of the Hagana underground in the 1920s
• Reuven Zelicovici (later Rubin), Romanian-born Israeli painter and Israel's first ambassador to Romania
• Antonina Zelikovich, Russian rower
• Miriam Eshkol (née Zelikovich), wife of Israeli Prime Minister Levi Eshkol

• Zeljković
• Ashkenazi Jews
• Jewish surnames
• German Jews