Tsukasa attended Tottori Prefectural Sakai High School and graduated from Kyoritsu Women's Junior College in 1954.[1][7] In the same year, she was scouted after appearing on the cover of Katei Yomiuri and signed with the Toho Studios.[1] She had her film debut in Kimi shinitamo koto nakare, replacing Ineko Arima due to illness.[1] She was given her stage name by her co-star Ryō Ikebe, and eventually decided to become an actress against her family's initial opposition.[1] Her most important films include Yasujirō Ozu's Late Autumn (1960) and The End of Summer (1961), Akira Kurosawa's Yojimbo (1961), Noboru Nakamura's The Kii River (1966) and Mikio Naruse's Scattered Clouds (1967).[1][8]
She married politician and attorney Hideyuki Aizawa (1919–2019) in 1969 and reduced her acting activities after 1971 to care for her family.[1][7] Their son Hiromitsu married singer and actress Shōko Aida.[9]
Tsukasa was head of the "Nihon Taishō Mura" (Japan Taisho Village) open air museum in Ena, Gifu Prefecture, from 1999 to 2015. In 2021, she was honoured with a memorial hall in Nihon Taishō Mura.[10]