The headwaters are at an elevation of about 1,250 feet[2] and the mouth is at an elevation of 863 feet.[1]
Whites Creek begins as a south flowing stream on the south side of Table Rock Knob just southeast of Ava and flows south for a short distance before turning east. The stream runs parallel to Missouri Route 14 and is bridged where the road turns south. Hoffmeister Spring emerges from a bluff along the north side of the stream a few hundred yards east of the bridge at 36°54′51″N92°33′12″W / 36.91417°N 92.55333°W / 36.91417; -92.55333 and an elevation of 892 feet.[3][4]
Whites Creek has the name of a pioneer citizen with the surname White.[5]