The white cerebellum sign, also known as reversal sign or dense cerebellum sign, is a radiological sign denoting the relatively white appearance of the cerebellum due to a generalized decrease in density of the supratentorial brain structures caused by extensive edema.[1]
Causes
White cerebellum sign can be associated with raised intracranial pressure[2] that occurs due to anoxic or ischemic changes in the brain.[3] It can be found in:
Diffuse brain edema is the likely cause of this radiological change observed in CT or MRI.[2]
Prognosis
It was considered to indicate a bad prognosis.[4] However, evidence suggests that it could be a non-specific indicator of diffuse brain edema which might not be as ominous as previously thought.[2]
