"What's the Difference" is a song by Dr. Dre.

What's the Difference may also refer to:

• What's the Difference?, a book by John Piper, later republished as part of Recovering Biblical Manhood and Womanhood
• What's the Difference, a 1986 TV movie about IVF starring Debra Lawrance
• "Eyelash Curlers & Butcher Knives (What's the Difference?)", a song by Jeffree Star

This disambiguation page lists articles associated with the title What's the Difference.
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