Vighizzolo d'Este is a comune (municipality) in the Province of Padua in the Italian region Veneto, located about 60 kilometres (37 mi) southwest of Venice and about 30 kilometres (19 mi) southwest of Padua.
Vighizzolo d'Este borders the following municipalities: Carceri, Este, Piacenza d'Adige, Ponso, Sant'Urbano, Villa Estense.
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