Vicente Lucio Salazar was born to Manuel María Salazar y Lozano and Carolina Cabal y Salazar on 20 December 1832 in Quito. He became a Juris Doctor and worked as an economist for thirty years, serving variously as the Minister of Finance in 1873, 1883, 1884-1887, 1888, and 1893.[2] He later served in the National Congress as a Deputy. In 1892 he was elected as the President of the Senate, and in 1893 was delegated by Luis Cordero to be the Minister of the Interior and Foreign Relations, but he was shortly thereafter elected as the Vice President. His president, though, was caught up in a controversy regarding the First Sino-Japanese War, called the Venta De La Bandera. Cordero resigned, leading to Lucio's presidency, which began on 16 April 1895. His presidency saw the beginning of the Liberal Revolution of Ecuador [es]. Meanwhile, he could not fulfill government obligations because of paralysis. This led to a resignation filed on 28 June 1895 (where he was succeeded by Eloy Alfaro) and later death on14 February 1896 in Quito.[3][4]
In his time as a finance minister, he went to Washington, D.C., on occasions to ask for loans from the United States.[5]