The 12741/Vasco da Gama–Patna SF Express has an average speed of 57 km/h and covers 2229 km in 39h 05m. The 12742/Patna–Vasco da Gama SF Express has an average speed of 58 km/h and covers 2229 km in 38h 15m.
On 24 November 2017, train number 12741 was derailed near platform number two of Manikpur railway station in Chitrakoot division, Uttar Pradesh.[5] The train was derailed at 4:18 am (IST), with three people getting killed and at least nine injured. One coach of the train was half tilted in the incident.[5] Seven injured were referred to the Manikpur CHC hospital while two were sent to the district hospital in Chitrakoot. According to ADG (Law and Order), Anand Kumar, "prima facie it appears that fractured railway track is the cause of accident as per local assessment".[6]