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UroVaxom

UroVaxom
Vaccine description
TargetEscherichia coli
Vaccine typeInactivated
Clinical data
Trade namesUroVaxom
Other namesOM-89; OM-8980
Routes of
administration		Oral (tablet)[1][2]

UroVaxom (developmental code names OM-89, OM-8980) is a vaccine against urinary tract infections (UTIs).[3][2][4] It is an extract of 18 strains of killed Escherichia coli administered as an oral tablet once daily for 3 months.[3][1][2] The vaccine is marketed for use in the prevention of recurrent UTIs in some European countries.[3][2] It was also being studied for treatment of prostatitis but was discontinued.[3] UroVaxom was initially developed in the 1980s.[5]

See also

References

  1. ^ a b Hughes T, Juliebø-Jones P, Saada L, Saeed K, Somani BK (December 2021). "Recurrent urinary tract infections in adults: a practical guide". British Journal of Hospital Medicine. 82 (12): 1–11. doi:10.12968/hmed.2021.0337. PMID 34983214.
  2. ^ a b c d O'Brien VP, Hannan TJ, Nielsen HV, Hultgren SJ (February 2016). "Drug and Vaccine Development for the Treatment and Prevention of Urinary Tract Infections". Microbiology Spectrum. 4 (1). doi:10.1128/microbiolspec.UTI-0013-2012. PMC 4887100. PMID 26999391.
  3. ^ a b c d "OM 8980". AdisInsight. 16 August 2022. Retrieved 26 February 2025.
  4. ^ Prattley S, Geraghty R, Moore M, Somani BK (May 2020). "Role of Vaccines for Recurrent Urinary Tract Infections: A Systematic Review". European Urology Focus. 6 (3): 593–604. doi:10.1016/j.euf.2019.11.002. PMID 31806578.
  5. ^ Huttner A, Gambillara V (October 2018). "The development and early clinical testing of the ExPEC4V conjugate vaccine against uropathogenic Escherichia coli". Clinical Microbiology and Infection. 24 (10): 1046–1050. doi:10.1016/j.cmi.2018.05.009. PMID 29803843.

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