UnaL2 LINE 3′ element

UnaL2 LINE 3′ element
Predicted secondary structure and sequence conservation of UnaL2
Identifiers
SymbolUnaL2
RfamRF00436
Other data
RNA typeCis-reg
Domain(s)Eukaryota
SOSO:0000233
PDB structuresPDBe

The UnaL2 LINE 3′ element is an RNA element found in the UnaL2 LINE (long interspersed nuclear element) and partner SINE (short interspersed nuclear element) from eel.[1] This conserved element is a stem-loop that is critical for their retrotransposition found in their 3′ end. The first step of retrotransposition is the recognition of their 3′ tails by UnaL2-encoded reverse transcriptase. The NMR structure of a 17-nucleotide RNA derived from the 3′ tail of UnaL2 has been determined.[1]

References

  1. ^ a b Baba S, Kajikawa M, Okada N, Kawai G (September 2004). "Solution structure of an RNA stem-loop derived from the 3′ conserved region of eel LINE UnaL2". RNA. 10 (9): 1380–1387. doi:10.1261/rna.7460104. PMC 1370625. PMID 15273327.
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