Los Angeles was recommissioned on 27 January 1951, Capt. Robert N. McFarlane in command. In response to the American efforts in the Korean War, she sailed for the Far East 14 May and joined naval operations off the eastern coast of Korea on 31 May as flagship for Rear Admiral Arleigh A. Burke's CRUDIV 5. During the next six months she ranged the coastal waters of the Korean Peninsula from Hungnam in the east to Haeju in the west while her guns pounded enemy coastal positions. After returning to the United States on 17 December for overhaul and training, she made her second deployment to Korean waters on 9 October 1952 and participated on 11 October in a concentrated shelling of enemy bunkers and observation points at Koji-ni. During the next few months, she continued to provide off-shore gunfire support for American ground operations, and cruised the Sea of Japan with fast carriers of the 7th Fleet. While participating in the bombardment of Wonsan late in March and early in April 1953, she received minor damage from enemy shore batteries, but continued operations until sailing for the west coast in mid-April. She arrived at Long Beach on 15 May.
1953–1963
Between November 1953 and June 1963 Los Angeles made eight more deployments to the Far East where she served as a cruiser division flagship with the 7th Fleet in support of "keeping the peace" operations in that troubled part of the world. Her operations sent her from the coast of Japan to the Sea of Japan, the Yellow Sea, and the East and South China Seas; and with units of the 7th Fleet she steamed to American bases in the Philippines and Okinawa, as well as to Allied bases in South Korea, Hong Kong, Australia, and Taiwan. During the Quemoy-Matsu crisis in 1956, she patrolled the Taiwan Strait to help protect ROC Army units from possible landing offenses from Communist China. When not deployed in the western Pacific, Los Angeles operated out of Long Beach along the west coast and in the Pacific to the Hawaiian Islands. She returned to Long Beach from her final Far East deployment on 20 June 1963.
Decommissioning and sale
While some consideration was made to convert Los Angeles into a single-end Talos missile cruiser, with flagship facilities (in essence a heavy cruiser version of the Oklahoma City) funds were not appropriated for this or for a general overhaul to enable her continued fleet service, so she was decommissioned at Long Beach on 15 November 1963 and entered the Pacific Reserve Fleet at San Diego. Stricken on 1 January 1974, and sold on 16 May 1975 (sale #16-5049) to the National Steel Corporation for $1,864,380.21, and scrapped in San Pedro, California.
An event to promote the July 1943 bond drive to finance the ship was held at the Hollywood Bowl on June 30, 1943. A recording of the event is available to stream on archive.org.
In a scene (approximately 47:40–53:00) from the 1977 film MacArthur depicting a Pearl Harbor shipboard strategy meeting between President Roosevelt, Nimitz, and MacArthur, a painting of the USS Los Angeles is clearly seen on the bulkhead.