By 1958, Ganea and his mentee, Israel Berstein [ro], were the two leading algebraic topologists in Romania.[4] Later that year at an international conference on geometry and topology in Iași, the two met Peter Hilton, starting long mathematical collaborations. Ganea left for France in 1961, where he obtained in 1962 his Ph.D. from the University of Paris under Henri Cartan,[3] with thesis Sur quelques invariants numeriques du type d'homotopie.[5] He then emigrated to the United States. After spending a year at Purdue University in West Lafayette, Indiana, he joined the faculty at the University of Washington in Seattle.[3]
Just before he died, Ganea attended the Symposium on Algebraic Topology, held February 22–26, 1971 at the Battelle Seattle Research Center, in Seattle.[6] At the symposium, he was not able to give a talk, but he did distribute a preprint containing a list of unsolved problems. One of these problems, regarding the Lusternik–Schnirelmann category, came to be known as Ganea's conjecture. A version of this conjecture for rational spaces was proved by Kathryn Hess in her 1989 MIT Ph.D. thesis.[7] Many particular cases of Ganea's original conjecture were proved, until Norio Iwase provided a counterexample in 1998.[8] A minimum dimensional counterexample to Ganea’s conjecture was constructed by Don Stanley and Hugo Rodríguez Ordóñez in 2010.[9]