Tsalenjikha is the birthplace of the famous Georgian poet, Terenti Graneli.
Georgi Tsurtsumia (born October 29, 1980), Georgian-Kazakh wrestler who competed in the Men's Greco-Roman 120 kg at the 2004 Summer Olympics and won the silver medal.
Antisa Khvichava (1880–2012), Supposedly the World's Oldest Person who claimed to have been born in 1880. died on 30 September 2012, purportedly at the claimed age of 132.