A Trendelenburg operation is a surgical procedure conducted for the treatment of varicose veins. It is the juxtafemoral flush ligation of the great saphenous vein to the femoral vein.^[1][2]

An oblique incision is made in the groin, over the femoral artery and extending 4 cm medially. The great saphenous vein is exposed and the common femoral and subsartorial veins are identified before dividing. The vein is ligated close to the junction with of the femoral vein.^[3] If the ligation is distal from the saphenofemoral junction, it will leave out small tributaries which may later cause recurrence of varicosities. Additionally, there is risk of a blind loop formation, which can be a potential space for the formation of thrombus. The rate of recurrence in this surgical procedure is high.^{[citation needed]}

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