TGen was established in July 2002 by Jeffrey Trent in Phoenix, Arizona, with an initial investment of US$100 million from Arizona public- and private-sector investors.[2]
The mission of TGen is to make and translate genomic discoveries into advances in human health.[3] TGen has contributed to the growth of scientific research and biotechnology in Arizona. The institute has been involved in collaborations and studies, such as the research on chronic traumatic encephalopathy (CTE) in former NFL players in partnership with Exosome Sciences.[4]