Thomas or Tom Leighton may refer to:

• Thomas Leighton (fl.1485), MP for Shropshire (UK Parliament constituency)
• Thomas Leighton (died 1600), MP for Shropshire
• Thomas Leighton (governor), died 1610, 16th century Governor of Guernsey and MP for Worcestershire
• Thomas Leighton (surgeon) (died 1848), surgeon to the general hospital of Newcastle-upon-Tyne
• Thomas M. Leighton, American politician

• All pages with titles containing Thomas Leighton
• Thomas Layton (disambiguation)

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