Thomas Henry Selby (May 14, 1820 – June 17, 1875) was an American politician and businessperson. He served as the 12th Mayor of San Francisco, from December 6, 1869 until December 3, 1871. He was the first Republican mayor of San Francisco.
When he was 29 years old, Selby went to California for the California Gold Rush. He moved to San Francisco, California and became a merchant in the city. Selby built the Selby Shot Tower in San Francisco and founded the Selby Smelting Works.
He was then elected mayor and served from December 6, 1869, to December 3, 1871.
Selby's daughter, Jeanie, married Faxon Dean Atherton Jr., a son of Atherton namesake Faxon Dean Atherton. His daughter Clair married Andrew Jackson Ralston, brother of William Chapman Ralston. His son, Prentiss, married Nattie Cofin of the Nantucket Cofins. His daughter, Cornelia, married Rear-Admiral Louis Kempff of Belleville, Ill.
