The Ties That Bind, or variants, may refer to:

• The Tie That Binds (1923 film), a lost American silent drama
• The Ties That Bind, a 1985 documentary by Su Friedrich
• The Tie That Binds (1995 film), a thriller starring Daryl Hannah
• Ties That Bind, a 2006 TV movie starring Nicole de Boer
• Ties That Bind, a 2010 TV movie starring Kristanna Loken
• Ties That Bind (film), a 2011 drama

• Street Fighter IV: The Ties That Bind, an animated movie tie-in of the video game Street Fighter IV
• The Suffering: Ties That Bind, a 2005 video game
• "Ties That Bind", a 2-part episode of The Walking Dead: A New Frontier

• The Ties That Bind, a 1993 BDSM novel by Vanessa Duriès
• The Ties That Bind, a novel in the Star Wars: Jedi Apprentice series
• Ties That Bind, a 1993 book by Guy Baldwin
• The Tie That Binds (novel), by Kent Haruf, 1984

• "Blest Be the Tie that Binds", a hymn by John Fawcett
• Ties That Bind, a scrapped album by Bruce Springsteen that led to The River, 1980
  • "The Ties That Bind" (Bruce Springsteen song), 1980
  • The Ties That Bind: The River Collection, a 2015 box set
• "The Ties That Bind" (Don Williams song), 1974
• "Ties That Bind", a song by Alter Bridge from the 2007 album Blackbird
• "Ties That Bind", a song by August Burns Red from the 2020 album Guardians
• "Ties That Bind", a song by Disarmonia Mundi from the 2009 album The Isolation Game
• "The Ties That Bind", a song by Kamelot from the 2015 album Haven Japanese edition
• "Tie That Binds", a song by Drake from the 2022 album Honestly, Nevermind

• Ties That Bind (TV series), a 2015 Canadian-American drama series
• "The Ties That Bind", an episode of Andromeda, 2000
• "The Ties That Bind", an episode of Arrow season 6, 2018
• "The Ties That Bind" (Battlestar Galactica), 2008
• "The Ties That Bind" (Jeeves and Wooster), 1993
• "The Ties That Bind", an episode of The O.C. season 1, 2004
• "The Ties That Bind", an episode of Justice League Unlimited, 2005
• "Ties That Bind", an episode of The Loud House, 2016
• "Ties That Bind", an episode of She-Ra and the Princess of Power, 2019
• "The Ties That Bind", an episode of Stargate SG-1 season 9, 2005
• "Ties That Bind", an episode of Xena: Warrior Princess season 1, 1996
• "The Ties That Bind" (The Vampire Diaries), 2012
• "Ties That Bind", an episode of Revolution, 2012
• "Ties That Bind Us", an episode of Hustle
• "The Ties That Bind", in Naruto volume 64, 2013
• "The Ties that Bind", an episode Kavanagh QC, 1997
• Ties That Bind, an episode of Beyond, 2017

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