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The sentence "Calcium released from the presynaptic neuron binds to a ligand-gated calcium channel in the postsynaptic neuron to stimulate an impulse in that neuron." is completely wrong. What happens is that calcium enters the presynaptic terminal as a result of the opening of voltage-dependent calcium channels following the arrival of the impulse. This causes neurotranmitter release. The transmitter binds to postsynaptic ligand-gated channels which open, and may cause postsynaptic depolarization and postsynaptic spiking.

In general, I am not sure that "uniporters" are the same as ion channels, as this article implies. 129.49.104.32 (talk) 19:25, 3 November 2009 (UTC)Reply

It appears this is just a protein that does uniport. Ion channels do it (passively), and there are carrier-mediated proteins that do it. So, it's a heterogenous group and thus largely irrelevant. Its just that the term is convenient. --SCIdude (talk) 13:15, 4 September 2019 (UTC)Reply

Uniporters are not the same as ion channels. The mechanism of transport is critical to the distinction of these two classes of proteins. The bulk flow of ions associated with ion channel proteins is different from the individual noncovalent binding of ions or other molecules to specific sites on a uniporter protein.Jgtokuhisa (talk) 22:55, 13 March 2021 (UTC)Reply

This article was the subject of a Wiki Education Foundation-supported course assignment, between 24 August 2020 and 1 July 2021. Further details are available on the course page. Student editor(s): MaireadL002. Peer reviewers: Putneyn4.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 09:36, 18 January 2022 (UTC)Reply

This article was the subject of a Wiki Education Foundation-supported course assignment, between 24 August 2023 and 8 December 2023. Further details are available on the course page. Student editor(s): Stellur (article contribs).

— Assignment last updated by MatthewGuareschi (talk) 19:56, 27 November 2023 (UTC)Reply