7103
216350
ENSG00000127324
ENSMUSG00000034127
P19075
Q8R3G9
NM_004616NM_001369760
NM_001168679NM_001168680NM_146010
NP_004607NP_001356689
NP_001162150NP_001162151NP_666122
Tetraspanin-8 is a protein that in humans is encoded by the TSPAN8 gene.[5][6]
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.[6]
Overall survival of ovarian cancer patients was effectively predicted by TSPAN8.[7]
This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.
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