Symmes can refer to:

• John Cleves Symmes, colonel in the Continental Army and New Jersey representative at the Continental Congress
• John Cleves Symmes, Jr., originator of the Hollow Earth theory
• Zechariah Symmes, Puritan minister in colonial Charlestown, Massachusetts

• Symmes Creek in southeastern Ohio
• Symmes Mission Chapel in Fairfield, Ohio
• Symmes Purchase in southwestern Ohio
• Symmes Township, Edgar County, Illinois
• Symmes Township, Hamilton County, Ohio
• Symmes Township, Lawrence County, Ohio
• Symmes Valley High School in Willow Wood, Ohio

This disambiguation page lists articles associated with the title Symmes.
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