Sweetwater Creek may refer to:

• Sweetwater Creek (novel), a novel by Anne Rivers Siddons
• Sweetwater Creek, Florida, an unincorporated community in Hillsborough County, Florida
• Sweetwater Creek (Chattahoochee River), Georgia
  • Sweetwater Creek State Park, in Douglas County, Georgia
• Sweetwater Creek (Echeconnee Creek tributary), Georgia
• Sweetwater Creek (Flint River tributary), Georgia
• Sweetwater Creek (Logan Creek), a stream in Missouri
• Sweetwater Creek (Comanche County, Texas)
• Sweetwater Creek (Gray County, Texas)
• Sweetwater Creek (Nolan County, Texas), namesake of Sweetwater, Texas
• Sweetwater Creek (Wise County, Texas)
• Sweetwater Creek (Tennessee River), tributary to the Tennessee River at Loudon, Tennessee
• Sweetwater Creek in Frankston, Victoria, Australia

• Sweetwater (disambiguation)
• Sweetwater River (disambiguation)

This disambiguation page lists articles associated with the title Sweetwater Creek.
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