Vaughn started his career in commercial litigation and shifted his career to trade law in the early 2000s.[6] He was a professor of law at Georgetown Law School.[7]
On March 2, 2017, due to the U.S. Senate's delay in confirming USTR nominee Robert Lighthizer, Trump appointed Vaughn to the position of USTR general counsel and elevated him to acting USTR.[6] Vaughn's appointment was likely the first time that someone from outside the department was appointed as acting USTR.[6] These appointments did not require Senate confirmation.[3][6]
Vaughn's positions on U.S. trade policy have been compared to those of Alexander Hamilton and Trump.[6]
On April 22, 2019, the USTR announced Vaughn would resign his position in the coming weeks.[1] Shortly after he returned to previous positions with King & Spalding. [9]
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