Stephen J. Challacombe

Stephen J. Challacombe
FRC(Path), FDSRCS, FMedSci
Professor Stephen Challacombe (2019)
BornApril 1946
NationalityBritish
EducationGuy's Hospital Dental School
Known for
SpouseTina
Children2
Scientific career
Fields
  • Oromucosal immunology
  • Global health inequalities
Institutions

Stephen James Challacombe (born April 1946) is professor of oral medicine at King's College in London, best known for research in oromucosal immunology and for developing the Challacombe scale for measuring the extent of dryness of the mouth. He led the team that laid out research challenges of global health inequalities and oral health, particularly relating to the oral manifestations of HIV.

Challacombe was the Martin Rushton Professor of Oral Medicine at King's College, London and the University of London, a consultant in diagnostic microbiology and immunology to Guys & St Thomas Hospitals, and Dean for external affairs at King's College London Health Schools.

He has been an author, co-author, editor and co-editor of a number of publications and a recipient of several awards and fellowships. Medical societies of which he has been president include the International Association for Dental Research, British Society for Oral and Dental Research, European Association of Oral Medicine and the Hunterian Society, and the world's oldest rugby club, Guy's Hospital RFC.

Early life

Stephen Challacombe was born in April 1946. He attended Culford School, where he played sports including rugby.[1]

Mucosal immunology

Challacombe initially worked in the field of immunology.[2] In 1978, he was appointed assistant professor and senior research fellow in the Department of Immunology at the Mayo Clinic in the United States,[3] and completed the fellowship in 1979.[4]

From 1984 to 2011, Challacombe was consultant in diagnostic microbiology and immunology to Guys & St Thomas Hospitals.[5] During this time, he became professor of oral medicine in the department of Oral Medicine and Pathology at Guy's Hospital in 1986 and the Martin Rushton Professor of oral medicine in 1988.[2][6]

Later career

Challacombe was appointed Director of External Strategy at the Dental Institute in 2005 and a year later became Dean for King's College London KCL External Affairs, holding both posts until 2011.[5][7]

His experience has also included coordinating conferences and university departments, managing grants, finances and research, and teaching.[3]

Challacombe scale

Challacombe developed the Challacombe scale for measuring the extent of dryness of the mouth in human beings. It was launched in 2011 at Tylney Hall in Hampshire[8] and has become widely used as a medical tool for assessing and monitoring dry mouth.[9][10][11]

Global oral health

Challacombe became involved in clinical research in oral HIV and AIDS, and has chaired international workshops on the oral manifestations of HIV infection in the UK, South Africa, Thailand, China, and India. In 1991 and 1993, he contributed to the consensus meeting on the classification of oral lesions in HIV.[1][3] He was chairman of the International Steering Committee on Oral Health and Disease in HIV infection between 2000 and 2017.[3]

In 2011, Challacombe led the team that laid out research challenges of global health inequalities and oral health, particularly relating to Noma, tuberculosis, sexually transmitted disease and HIV, four of the most serious global oral health infections.[12][13][14] With regards to clinical signs in the mouth in AIDS, he identified a significant role for dentists.[13]

Later, using Sierra Leone as a case study to develop oral health programmes in low-income countries, he worked with the King's Sierra Leone Partnership's dentistry section,[15] as a member of The Kings Centre for Global Health.[1]

In 2020, he co-authored a review which proposed using povidone-iodine to reduce cross-infectivity of COVID-19,[16] and highlighted the role of saliva in the transmission of the disease.[17]

History of medicine

As a historian of medicine, his lectures have included a series on the London medical students at Belsen.[18]

Awards and honours

Awards

Challacombe is a recipient of a number of awards including:

  • Colgate (Hatton) Research Prize, British Division, IADR (1977)[5]
  • Kendall-Hench Research Fellowship, Mayo Clinic, Minnesota, USA (1978)[5]
  • Basic Research in Oral Science Award, IADR. (1981)[5]
  • Distinguished Scientist Award for Experimental Pathology, IADR, (1997)[5]
  • DSc (h.c.), University of Athens (2012)[5]
  • American Academy of Oral Medicine Samuel Charles Miller award (2018)[5][19]
  • Distinguished Alumni Award of the Mayo Clinic (2017).[4]

Presidencies

Stephen Challacombe, Hunterian Society (October 2019)

He has been president of:

He has also been president of the world's oldest rugby club, Guy's Hospital RFC.[1][20]

Chairmanships

He was chairman of:

Fellowships

He is a fellow of the:

Personal life

He is married to Tina and they have two children.[1]

In 2013, he joined the Board of Governors of Culford School.[1] He also continues to support students of the world's oldest rugby club, Guy's Hospital RFC.[22]

Writing

He has been an author, co-author, editor and co-editor of a number of publications including nine books, over 240 peer-reviewed research papers and 160 other works on various aspects of oral and maxillofacial medicine.[3] These have included publications on induction of secretory immune responses, oral tolerance and on immunological aspects of the oral cavity.[2] His interest on mucosal immunity in HIV and how HIV can present with signs in the mouth, has resulted in over 25 research articles.[3]

Selected publications

Articles

Books

References

  1. ^ a b c d e f "Culford School; Meet the Governors". www.culford.co.uk. Retrieved 23 May 2020.
  2. ^ a b c Challacombe, S.; Bland, P.; Stokes, C.; Heatley, A.; Mowat, A. (1990). Advances in Mucosal Immunology: Proceedings of the Fifth International Congress of Mucosal Immunology. Springer Science & Business Media. ISBN 0-7462-0113-3.
  3. ^ a b c d e f "World Workshop - Global Overview of HIV". ww8aids.org. Faculty of Dentistry Universitas Padjadjaran. 2018. Retrieved 26 June 2019.
  4. ^ a b "Mayo Clinic announces 2017 Distinguished Alumni Awards". newsnetwork.mayoclinic.org. Retrieved 26 June 2019.
  5. ^ a b c d e f g h i j k l m n o p q r s t u v "Professor Stephen Challacombe". www.kcl.ac.uk. Retrieved 25 June 2019.
  6. ^ a b "Stephen Challacombe". Linked in. Retrieved 30 July 2019.
  7. ^ "In Touch Autumn 2013". Issuu. Retrieved 11 July 2019.
  8. ^ "Dry mouth scale launched". British Dental Journal. 211 (8): 351. 21 October 2011. doi:10.1038/sj.bdj.2011.884. ISSN 1476-5373.
  9. ^ Meurman, Jukka H. (2018). Translational Oral Health Research. Springer. p. 15. ISBN 978-3-319-78204-1.
  10. ^ Katz, James D.; Walitt, Brian (2018). Rheumatic Diseases in Older Adults, An Issue of Rheumatic Disease Clinics of North America E-Book. Elsevier Health Sciences. p. 426. ISBN 9780323613545.
  11. ^ Banerjee, Avijit; Watson, Timothy F. (2015). Pickard's Guide to Minimally Invasive Operative Dentistry. Oxford University Press. ISBN 9780198712091.
  12. ^ Challacombe, S.; Chidzonga, M.; Glick, M.; Hodgson, T.; Magalhães, M.; Shiboski, C.; Owotade, F.; Ranganathan, R.; Naidoo, S. (May 2011). Williams, D.M. (ed.). "Global Oral Health Inequalities: Oral Infections–Challenges and Approaches". Advances in Dental Research. 23 (2): 227–236. doi:10.1177/0022034511402081. ISSN 0895-9374. PMID 21490235. S2CID 5256917.
  13. ^ a b Wilson, Nairn; Dunne, Stephen (2018). Manual of Clinical Procedures in Dentistry. John Wiley & Sons. p. 30. ISBN 9780470670521.
  14. ^ Tappuni, A. R.; Shiboski, C. (2016). "Overview and research agenda arising from the 7th World Workshop on Oral Health and Disease in AIDS" (PDF). Oral Diseases. 22 (S1): 211–214. doi:10.1111/odi.12459. ISSN 1601-0825. PMID 27109289.
  15. ^ "Dentistry – King's Sierra Leone Partnership". Retrieved 11 July 2019.
  16. ^ Vlessides, Michael (12 June 2020). "Can Mouthwash Douse the Spread of COVID-19?". Medscape. Retrieved 5 July 2020.
  17. ^ "Joint international virtual seminar: Saliva as an important body fluid in the COVID-19 pandemic". www.kcl.ac.uk. Retrieved 3 October 2020.
  18. ^ Burns, Judith (15 April 2020). "The medical students who saved lives at Belsen". BBC News. Retrieved 23 May 2020.
  19. ^ "History of Awards - Samuel Charles Miller". www.aaom.com. Retrieved 26 June 2019.
  20. ^ "Guys Rugby". 9 April 2009. Archived from the original on 9 April 2009. Retrieved 10 July 2019.
  21. ^ "Fellowship for Professor Challacombe". British Dental Journal. 209 (5): 202. 11 September 2010. doi:10.1038/sj.bdj.2010.782. ISSN 1476-5373. S2CID 33400233.
  22. ^ "King's College London Association / KCLA Sports Dinner". www.kcla.co.uk. Retrieved 26 June 2019.

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