Spring viraemia of carp, also known as swim bladder inflammation, is caused by Carp sprivivirus, also called Rhabdovirus carpio. It is listed as a notifiable disease under the World Organisation for Animal Health.
Clinical symptoms of viral infection include external hemorrhaging, pale gills, and ascites.[3] In some cases, mortality can occur without any apparent clinical signs of the disease.[4] The virus has been found in high concentrations in the liver and kidney, but lower numbers of virions have been isolated from the spleen.[5] The virus has been shown to persist subclinically in fish populations up to 10 weeks following experimental infection.[1] Currently efforts have been made to prevent infection by the virus through the development of DNA vaccines[6] and immunostimulatory therapeutics.[7]
Prevalence
The virus has been implicated in several outbreaks of SVC throughout the past few decades. Originally the range of the virus was isolated to Europe and the Middle East. In 2002 it was isolated from a North Carolina lake.[8] In 2004 the virus was isolated from imported koi in Cedar Lake, Wisconsin.[9] Additionally, the virus has been linked to an outbreak of SVC in 2006 at Hamilton Bay in Lake Ontario.[10]
^Fijan, N; Petrinec Z; Sulimanovic D; Zwillenberg LO (1971). "Isolation of the viral causative agent from the acute form of infectious dropsy of carp". Veterinary Archives. 41: 125–138.
^Fisal, M; Ahne W (1984). "Spring viremia of carp virus (SVCV): comparison of immunoperoxidase, fluorescent antibody and cell culture isolation techniques for detection of antigen". Journal of Fish Diseases. 7 (1): 57–64. Bibcode:1984JFDis...7...57F. doi:10.1111/j.1365-2761.1984.tb00906.x.
^Dikkeboom, A; et al. (2004). "First Report of Spring Viremia of Carp Virus (SVCV) in Wild Common Carp in North America". Journal of Aquatic Animal Health. 16 (4): 169–178. Bibcode:2004JAqAH..16..169D. doi:10.1577/H03-064.1.
^Garver, K; et al. (2007). "First detection and confirmation of carp virus in common carp, Cyprinus carpio L., from Hamilton Harbour, Lake Ontario, Canada". Journal of Fish Diseases. 30 (11): 665–671. doi:10.1111/j.1365-2761.2007.00851.x. PMID17958610.