The following is a list of spouses of holders of the position of president of the Philippines.

Customarily, the wife or husband of the president held the title of First Lady or First Gentleman serving functional role at the Malacañang Palace. Hence the titles are also erroneously used to refer to the president's spouse.

Three spouses, that of Elpidio Quirino, Diosdado Macapagal and Corazon Aquino, were already deceased at the start of their respective partner's presidencies although Macapagal was married to his second wife at the start of his presidency.

In the case of Rodrigo Duterte, his marriage with Elizabeth Zimmerman was already annulled at the start of his presidency. Duterte had another partner, Cielito Avanceña his common-law wife.

Benigno Aquino III is the only unmarried president.

Portrait	Spouse [note 1]	Marriage		President [note 2]
		Start	End
	Hilaria del Rosario (1877–1921)	1896	1921	Emilio Aguinaldo
	María Agoncillo (1879–1963)	1930	1963	Emilio Aguinaldo
	Aurora Aragón (1888–1949)	1918	1944	Manuel L. Quezon
	Pacencia Hidalgo (1889–1960)	1911	1959	José P. Laurel
	Estefania Veloso (1875–1918)	1901	1918	Sergio Osmeña
	Esperanza Limjap (1894–1978)	1920	1961	Sergio Osmeña
	Trinidad de Leon (1899–1995)	1921	1948	Manuel Roxas
	Alicia Syquia (1903–1945)	1921	1945	Elpidio Quirino
	Luz Banzon (1914–2004)	1933	1957	Ramon Magsaysay
	Leonila Dimataga (1906–1994)	1933	1971	Carlos P. Garcia
	Purita de la Rosa (1916–1943)	1938	1943	Diosdado Macapagal
	Evangelina Macaraeg (1915–1999)	1946	1997	Diosdado Macapagal
	Imelda Romualdez (born 1929)	1954	1989	Ferdinand Marcos Sr.
	Benigno Aquino Jr. (1932–1983)	1954	1983	Corazon Aquino (née Cojuangco)
	Amelita Martinez (b. 1927)	1954	2022	Fidel V. Ramos
	Loi Pimentel (born 1930)	1959	—	Joseph Estrada m. 1959
	Jose Miguel Arroyo (born 1945)	1968	—	Gloria Macapagal (Mrs. Arroyo)
	Elizabeth Zimmerman (born 1948)	1973	2000 Civilly annulled	Rodrigo Duterte
	Honeylet Avanceña (born 1970)	Not marriage, as Partner 2005	—	Rodrigo Duterte
	Liza Araneta (born 1959)	1993	—	Bongbong Marcos

• Entries in dark grey denotes spouses who were not married during their partner's presidencies either due to their death, their marriage that had been nullified, or they would be married after their partner's presidency.
• Benigno Aquino III has never been married.