South Carolina Highway 73 (SC 73) was a primary state highway in the U.S. state of South Carolina. Established five times in the state, from 1926 to 2006, its last routing was along Ocean Boulevard, in Myrtle Beach, a popular stretch of road lined with hotels, shops, tourist sites and access to the beach.
Ocean Boulevard is a major point during the annual Bi-Lo Marathon; full and half marathon runners head south during the first loop of the course, and for full marathon runners only, they head northbound for the second loop. Together, about nine miles (14 km) of the entire marathon course is run on Ocean Boulevard.
SCDOT handed SC 73 over to the city of Myrtle Beach in the 1990s and is no longer an official state route. As such, the route is no longer signed and, as of 2008, the route no longer appears on the official state highway map.