It has been classed as being in "moderate condition" by Melbourne Water,[1] but it is becoming increasingly urbanised as new developments extend across the catchment from Hoppers Crossing and surrounding areas. This new development poses a major risk to the health of the river, as does the poor quality of both the creek's water and streamside vegetation along significant parts of the waterway.
A recent defence force study of PFAS contamination on defence bases has indicated some groundwater contamination from sites at the partially decommissioned Williams Landing airforce base. Hydrological studies show that this groundwater flows into Skeleton Creek, and caution should be taken with consuming fish and eels from this creek.
See also
Skeleton Creek Trail, a cycling and walking trail along the southern part of the creek.