Sisile Khumalo (died 1875), was Ndlovukati (queen mother) of Swaziland during the reign of Dlamini IV.[1] Her son, Ludvonga, died poisoning without heirs in 1872 and was never made king.[1]
Khumalo was influential in the choice of Mbandzeni (later Dlamini IV) as successor to King Mswati II.[2]
Khumalo was executed after quarrelling with Dlamini IV.[1]