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Sespia; Temporal range: Late Oligocene
	Sespia californica fossils in San Diego
Scientific classification
Domain:	Eukaryota
Kingdom:	Animalia
Phylum:	Chordata
Class:	Mammalia
Order:	Artiodactyla
Family:	†Merycoidodontidae
Tribe:	†Sespiini
Genus:	†Sespia; Schultz & Falkenbach 1968
Type species
	†Leptauchenia nitida;
Species
	†S. nitida; †S. californica; †S. heterodon; †S. ultima;
Synonyms
	†Megasespia Schultz and Falkenbach, 1968;

Sespia ("of Sespe Creek") is an extinct genus of oreodont endemic to North America. They lived during the Late Oligocene 26.3—24.8 mya, existing for approximately 1.5 million years.^[1] Sespia was cat to goat-sized and desert-dwelling.^{[citation needed]} The genus was closely related to the larger Leptauchenia.

Restoration of *S. nitida* as a semi-aquatic animal, 1913

Fossils of the best known species, the cat-sized S. californica, have been found California and are known from literally thousands of specimens. The largest species, the goat-sized S. ultima, is known from late Oligocene deposits in Nebraska. S. ultima was once placed in a separate, monotypic, genus as Megasespia middleswarti. Other species were once placed within Leptauchenia.