Senator Gillespie may refer to:

• Ann Gillespie (politician) (fl. 2010s–2020s), Illinois State Senate
• James Gillespie (U.S. politician) (1747–1805), North Carolina State Senate
• James J. Gillespie (1892–1959), Iowa State Senate
• Jerry Gillespie (politician) (1950–2011), Arizona State Senate
• Joseph Gillespie (1809–1885), Illinois State Senate

This disambiguation page lists articles associated with the title Senator Gillespie.
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