Senator Clarke may refer to:

• James Paul Clarke (1854–1916), U.S. Senator from Arkansas from 1903 to 1916
• John Hopkins Clarke (1789–1870), U.S. Senator from Rhode Island from 1847 to 1853

• Archibald S. Clarke (1788–1821), New York State Senate
• Eugene Clarke (born 1956), Mississippi State Senate
• Frank Gay Clarke (1850–1901), New Hampshire State Senate
• George L. Clarke (1813–1890), Rhode Island State Senate
• George W. Clarke (Washington politician) (1906–2006), Washington State Senate
• Hansen Clarke (born 1957), Michigan State Senate
• James M. Clarke (1917–1999), North Carolina State Senate
• John Blades Clarke (1833–1911), Kentucky State Senate
• John Jones Clarke (1803–1887), Massachusetts State Senate
• John Clarke (Michigan politician) (1797–1876), Michigan State Senate
• Kathryn Clarke (politician) (1873–1940), Oregon State Senate
• S. D. Clarke (1881–1966), Florida State Senate
• Terrel E. Clarke (1920–1997), Illinois State Senate

This disambiguation page lists articles associated with the title Senator Clarke.
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