Senator Byrnes may refer to:

• James F. Byrnes (1882–1972), South Carolina State Senate
• John W. Byrnes (1913–1985), Wisconsin State Senate
• Jo Byrns (1869–1936), Tennessee State Senate
• Samuel Byrns (1848–1914), Missouri State Senate

• Senator Burns (disambiguation)
• Senator Byrne (disambiguation)

This disambiguation page lists articles associated with the title Senator Byrnes.
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