Senator Armstrong may refer to:

• Henry Armstrong (Northern Ireland politician) (1844–1943), Northern Irish Senator from 1921 to 1937
• Robert Armstrong (Northern Ireland politician) (1888/1889–1961), Northern Irish Senator from 1956 to 1961

• David H. Armstrong (1812–1893), U.S. Senator from Missouri
• John Armstrong Jr. (1758–1843), U.S. Senator from New York
• William L. Armstrong (1937–2016), U.S. Senator from Colorado

• George C. Armstrong (1872–1950), Illinois State Senate
• Gibson E. Armstrong (born 1943), Pennsylvania State Senate
• Harry Armstrong (politician) (1915–2011), Ohio State Senate
• James Armstrong (Texas politician) (1811–1879), Texas State Senate
• Kelly Armstrong (born 1976), North Dakota State Senate
• Samuel Turell Armstrong (1784–1850), Massachusetts State Senate
• Thomas H. Armstrong (1829–1891), Minnesota State Senate
• Thomas Armstrong (New York politician) (1785–1867), New York State Senate
• William W. Armstrong (politician) (1864–1944), New York State Senate

• Senator Armstrong (Metal Gear), the main antagonist of video game Metal Gear Rising: Revengance

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