The city was founded on 26 September 1735 by the viceroy Juan Antonio de Vizarrón y Eguiarreta as a Spanish garrison in order to protect them from the constant native attacks.[2][3] The name of the settlement was firstly called Santa Rosa María del Sacramento, name that was approved by the viceroy on 29 August 1737. On 6 February 1850, the settlement's name was abolished and it was renamed to Villa de Múzquiz, honoring the interim President Melchor Múzquiz.[3] On March 9 1925, Villa de Múzquiz was declared a city and its name changed to the current Melchor Múzquiz.[3] Her "ciudades amigas" was established with Denton, Texas in 2015.[4] Múzquiz was declared part of the "Pueblos Mágicos" touristic program in 2018.[2]
