Santa Cruz, Arizona Hia-t-ab (O'odham)
CDP
Location of Santa Cruz in Pinal County, Arizona.
Santa Cruz, Arizona Location in Arizona
Coordinates: 33°13′58″N 112°9′34″W / 33.23278°N 112.15944°W / 33.23278; -112.15944
Country	United States
State	Arizona
County	Pinal
Area [1]
• Total	1.63 sq mi (4.22 km2)
• Land	1.63 sq mi (4.22 km2)
• Water	0.00 sq mi (0.00 km2)
Population  (2020)
• Total	39
• Density	23.94/sq mi (9.25/km2)
Time zone	UTC-7 (MST (no DST))
ZIP code	85339[2]
Area code	520
FIPS code	04-63960

Santa Cruz (O'odham: Hia-t-ab) is a census-designated place (CDP) in Pinal County, Arizona, United States, located in the Gila River Indian Community. The population was 37 at the 2010 census.

As of the census^[4] of 2010, there were 37 people living in the CDP. The population density was 22.7 people per square mile. The racial makeup of the CDP was 97% Native American and 3% from other races. 8% of the population were Hispanic or Latino of any race.