Santa Clara Island is a small, rocky and cliffed island lying at the entrance of the Gulf of Guayaquil, off the Pacific coast of Ecuador. Geologically, it is formed of sedimentary rock and is situated on the transition zone between the relatively shallow and brackish waters of the gulf and the deeper marine waters of the open ocean. It has an area of 46 ha. Though currently uninhabited, it contains archaeological remains and is sacred to the inhabitants of nearby Puná Island. It lies some 25 km south-west of Puná and 43 km west of the city of Puerto Bolívar.