Taylor made his debut in Round 11, 2018, against Adelaide. He played nearly a full season in 2019, including making an appearance in GWS's first-ever (albeit unsuccessful) AFL Grand Final.
In the COVID-affected2020 season, after just four games for the year, Taylor was admitted to hospital with what was later diagnosed as septic arthritis in his pelvis and ankle. He was initially only expected to miss a month of football, but he ended up not playing for the rest of the season.[6][7][8]
Taylor played from the start of 2021, but he had a six-game break after Round 10 due to an ankle injury.[9][10]
Taylor played 22 out of 23 games in 2022, but a hamstring injury in 2023 saw him miss seven games.[11]
In Round 5, 2024, Taylor was knocked out cold, causing the game to be paused for about ten minutes until he was subbed out on a medicab. The Age’s Andrew Wu wrote: "Sam Taylor is as brave a player as they come. Broadcasters not showing a replay for good reason. Genuinely frightening stuff."[12] GWS's head of football, Jason McCartney, provided an update on Taylor following the quarter-time break: "He’s been taken to Canberra hospital for further assessment[,] but he was conscious and speaking as he got in the ambulance. Obviously it didn’t look great, but he’s a courageous kid and he’s in the very best hands and he’ll be fine."[13]
^The 2020 season was played with 17 home-and-away matches per team (down from 22) and 16-minute quarters with time on (down from 20-minute quarters with time on) due to the impact of the COVID-19 pandemic.