Saint Serena may be:

• Serena of Rome - (3rd century), legendary figure, erroneously believed to be the wife of Diocletian, celebrated on August 16
• Serena of Spoleto [de] - (4th century), martyr in Spoleto, celebrated on December 7

Geography

• Santa Serena [it] , toponym in the town of Schizzanello [it] in the Roma Capitale.

• Serena (given name)
• Serena (disambiguation)

This disambiguation page lists articles associated with the title Saint Serena.
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