Saiko may refer to:

• Saikō, a Japanese era
• Saiko, a Spanish singer
• Saiko (band), a Chilean rock band
• Saiko Lake, in Yamanashi Prefecture, Japan

• Ema Saikō (江馬 細香, 1787–1861), Japanese painter, poet and calligrapher
• Jean-Philippe Saïko (born 1990), New Caledonian footballer
• Shaun Saiko (born 1989), Canadian soccer player
• Saiko Takahashi (高橋 彩子, born 1976), Japanese women's footballer

• Psycho (disambiguation)
• Saikot, a village in Uttarakhand, India
• Seiko (disambiguation)

This disambiguation page lists articles associated with the title Saiko.
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