She was built by AG Vulcan of Hamburg and following just under a year of construction, launched at Hamburg on 9 June 1917. UB-64 was commissioned later that same year under the command of Kptlt.Otto von Schrader.
Like all Type UB III submarines, UB-64 carried 10 torpedoes and was armed with a 8.8 cm (3.46 in) deck gun. UB-64 would carry a crew of up to 3 officer and 31 men and had a cruising range of 8,420 nautical miles (15,590 km; 9,690 mi). UB-64 had a displacement of 508 t (500 long tons) while surfaced and 639 t (629 long tons) when submerged. Her engines enabled her to travel at 13.3 knots (24.6 km/h; 15.3 mph) when surfaced and 8 knots (15 km/h; 9.2 mph) when submerged.
^Helgason, Guðmundur. "WWI U-boat commanders: Walter Gude". German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. Retrieved 4 February 2015.
^Helgason, Guðmundur. "WWI U-boat commanders: Woldemar Petri". German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. Retrieved 4 February 2015.
^Helgason, Guðmundur. "WWI U-boat commanders: Ernst Krieger". German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. Retrieved 4 February 2015.
^Helgason, Guðmundur. "Ships hit by UB 64". German and Austrian U-boats of World War I - Kaiserliche Marine - Uboat.net. Retrieved 5 December 2014.