SDSS may refer to:

• Sloan Digital Sky Survey, a major multi-filter imaging and spectroscopic redshift survey
• Social Democratic Party of Slovakia
• Spatial Decision Support System, a GIS based decision aiding system
• Independent Democratic Serb Party, a political party of Croatian Serbs (Samostalna demokratska srpska stranka in Serbo-Croatian)
• South Delta Secondary School, a school in Delta, British Columbia, Canada

This disambiguation page lists articles associated with the title SDSS.
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