Following the 2011 season, Verdugo was traded by the Giants to the Kansas City Royals with Jonathan Sánchez for Melky Cabrera.[1] He was added to the Royals' 40-man roster on November 18 to protect him from the Rule 5 draft.[2] Verdugo made his major-league debut on July 17, 2012, against the Seattle Mariners. He allowed six runs in 1+2⁄3 innings, including an RBI double to Jesus Montero and a two-run home run to Justin Smoak, and picked up the loss.[3] The left-hander fared better after being sent down to Triple-A Omaha, posting a season record of 12–4 with a 3.75 ERA in 24 starts. Verdugo was designated for assignment by the Royals on November 20, 2012 as they cleared room on the 40-man roster ahead of the Rule 5 draft.[4] He was subsequently outrighted to AAA.
On July 16, 2014, Verdugo was traded to the Boston Red Sox in exchange for cash considerations.[6]
Oakland Athletics
On November 20, 2014, Verdugo, along with LHP Jim Fuller, signed a minor league contract with the Oakland Athletics organization.[7] He began the season with the Triple-A Nashville Sounds.
Los Angeles Angels
On July 6, 2015, Verdugo was traded to the Los Angeles Angels organization, where he played for the Triple-A Salt Lake Bees. On November 6, 2015, Verdugo elected free agency.
On February 14, 2018, Verdugo signed with the Uni-President Lions of the Chinese Professional Baseball League.[8] On October 7 of the same year, Verdugo completed the first (and, to date, only) perfect game in CPBL history.[9] He re-signed with the Uni-Lions for the 2019 season,[10] at the conclusion of which he became a free agent.
Mexican League (second stint)
On February 11, 2020, Verdugo signed with the Acereros de Monclova of the Mexican League. Verdugo did not play in a game in 2020 due to the cancellation of the Mexican League season because of the COVID-19 pandemic.[11] Verdugo re-signed with the team for the 2021 season. In 11 appearances, he posted a 14.49 ERA and gave up 34 hits over 13.2 innings pitched. On July 19, 2021, Verdugo was loaned to El Águila de Veracruz (previously known as the Rojos del Águila de Veracruz) of the Mexican League for the remainder of the 2021 season.[12] He was returned to Monclova following the conclusion of the season. On October 13, 2021, Verdugo, along with IF Jose Vargas and P Andrew Morales, were traded to the Saraperos de Saltillo of the Mexican League in exchange for OF Juan Perez.[13] On July 28, 2022, Verdugo was traded to the Toros de Tijuana.
On February 24, 2023, Verdugo's rights were re-acquired by El Águila de Veracruz of the Mexican League.[14] However, he did not appear for Veracruz, and retired from professional baseball on March 11, 2024.[15]
^"Naranjeros llega a 10 triunfos en LMP" [Naranjeros reach 10 wins in the LMP] (in Spanish). ESPN Deportes. Associated Press. October 25, 2013. Retrieved July 17, 2014.