In 2012, after missing out on signing a pro contract with Nancy, he was on trial with Ligue 2 club Boulogne but he tore his quadriceps and was injured for three months.[3][7] After recovering from his setback, Camacho would join fourth division club Lyon-Duchère.[8]
In 2014, he moved to fellow fourth division side Sedan, captaining them the following year after their promotion to the Championnat National.[9][10]
In March 2018, he signed with Canadian club Montreal Impact in Major League Soccer.[15][16] After starting in the first three games for his new club in which he was able, Camacho was sidelined with hip inflammation, causing him to miss the following six games.[17] He scored his first goal for his new club on 6 July 2019 in a 3–2 loss to Minnesota United.[18] In 2021, he was named the team's Defensive Player of the Year.[19] In February 2022, he extended his contract with the club until the end of the 2023 season.[20]
On 31 July 2023, Camacho was traded to fellow Major League Soccer side Columbus Crew in exchange for $400,000 in General Allocation Money.[21] Camacho would go on to win MLS Cup with his new side, earning a two-year contract extension after the victory.[10]
^Levesque, Dave (11 April 2018). "Rudy Camacho n'a jamais douté" [Rudy Camacho never doubted]. TVA Sports (in Canadian French). Archived from the original on 6 June 2024. Retrieved 6 June 2024.
^Levesque, Dave (8 June 2018). "Rudy Camacho est enfin en pleine forme" [Rudy camacho is finally in great shape]. TVA Sports (in Canadian French). Retrieved 6 June 2024.